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The efficacy of the available FDCs were evaluated in long-term studies in patients with T2DM on metformin monotherapy and treated with diet and exercise
[49] reported that the levels of 8-isoprostaglandin F2 (one of the major isoprostanes) in serum and synovial fluid were higher in OA patients compared to control subjects
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Dose ranges in cell work generally run from low nanomolar to low micromolar
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